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![]() The mean duration of clinical follow-up was 12 months (range, 4-24), and the local control rate was 100%. ![]() FF GKRS was performed based on a thermoplastic mask system for 3 to 5 consecutive days. We investigated the preliminary outcome of efficacy and toxicity associated with frameless fractionated gamma knife radiosurgery (FF GKRS) for the treatment of large metastatic brain tumors.įifteen patients with 17 lesions were treated using FF GKRS and included in this study, because of the large tumor size of more than 10 cm 3. ![]() Recently, a new generation of gamma knife radiosurgery (GKRS) equipped with a frameless immobilization system has encouraged the use of fractionated GKRS as an increasingly favorable treatment option.
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